Adele’s “21″ sells 10 million, Rihanna leads Billboard












LOS ANGELES (Reuters) – British singer and Grammy darling Adele reached the 10 million sales mark in the United States on Wednesday with her heartbreak album “21″ becoming the first by British woman to reach the milestone, Nielsen SoundScan said.


“21,” released in February 2011, produced the hits “Someone Like You” and “Rolling In The Deep” and became the top-selling album of 2011. Earlier this year, Adele swept the Grammy Awards with six, including song, record and album of the year.












“21″ became the third album to cross 10 million in 2012, along with Linkin Park‘s “Hybrid Theory” and Usher’s “Confessions.” But it is the only album to reach the milestone in less than two years in the last decade, Nielsen said.


“What an incredible honor,” Adele said in a statement. “A huge, huge thank you to my American fans for embracing this record on such a massive level.”


“21″ will receive the diamond certification from the Recording Industry Association of America, marking its 10 million milestone, joining the ranks of albums by artists such as Michael Jackson, The Beatles and Madonna.


Adele‘s unique talent is a gift to music fans, and her success is certainly cause for a celebration of Diamond magnitude,” Cary Sherman, RIAA’s chairman & CEO, said in a statement.


Adele, 24, is enjoying the success of her latest single “Skyfall,” the official theme song for the James Bond film of the same name. It has sold more than 2 million copies worldwide. The singer also gave birth to her first child earlier this year.


On the Billboard 200 chart this week, R&B star Rihanna scored her first No. 1 album with “Unapologetic,” selling 238,000 copies.


She held off new entries from “American Idol” winner Phillip Phillips, who landed at No. 4 with his debut album “The World From the Side of the Moon,” and country-rock singer Kid Rock, who rounded out the top five with his latest album “Rebel Soul.”


(Reporting By Piya Sinha-Roy Editing by Jill Serjeant, Grant McCool and Andre Grenon)


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Former baseball star Doug DeCinces indicted for insider trading












(Reuters) – Former Baltimore Orioles third baseman Doug DeCinces has been indicted by a federal grand jury for insider trading, the Justice Department said on Wednesday.


DeCinces was charged with 42 counts of criminal securities fraud and one count of money laundering over the 2008 purchase of stock in a medical device company based on insider information, according to an indictment filed in a federal court in Southern California.












DeCinces, 62, bought $ 160,000 worth of stock in Advanced Medical Optics Inc, after a “close personal friend” alerted him to an impending takeover bid by Abbott Laboratories, according to prosecutors.


He sold his stock shortly after the takeover bid was announced, making $ 1.3 million in profits, the department said.


A lawyer for DeCinces did not immediately respond to requests for comment.


The criminal charges came on the heels of civil charges filed against DeCinces in August 2011 by the Securities and Exchange Commission related to the same accusations.


DeCinces settled those charges with the SEC, agreeing to pay $ 2.5 million in fines, while neither admitting nor denying wrongdoing in the trading of Advanced Medical Optics shares.


The indictment also names three friends of DeCinces to whom he provided the insider information to make up for previous investment advice that “had gone bad,” according to prosecutors.


The others indicted are David Parker and Fred Scott Jackson, each charged with six counts of securities fraud. A third friend, Roger Wittenbach, faces four securities fraud charges. Parker also faces a money laundering charge.


The securities fraud charges carry a maximum sentence of 20 years imprisonment each, while the money laundering charges carry a 10-year maximum sentence for each count.


The four men charged are scheduled to appear in the U.S. District Court in Santa Ana, California, on December 17.


(Reporting by Mary Slosson; Editing by Cynthia Johnston and Eric Walsh)


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Numbers drawn for record Powerball jackpot


CHICAGO (AP) -- The numbers have been drawn for the record Powerball jackpot and the wait for winners — if any — has begun.

The numbers drawn Wednesday night are: 5, 16, 22, 23, 29 and Powerball of 6.

A lottery official said late Wednesday that the jackpot increased to $579.9 million by the time of the drawing, making the cash option $379.8 million.

Americans went on a ticket-buying spree in recent days, the big money enticing many people who rarely, if ever, play the lottery to purchase a shot at the second-largest payout in U.S. history.

Among them was Lamar Fallie, a jobless Chicago man who said his six tickets conjured a pleasant daydream: If he wins, he plans to take care of his church, make big donations to schools and then "retire from being unemployed."

Tickets were selling at a rate of 130,000 a minute nationwide — about six times the volume from a week ago. That meant the jackpot could climb even higher before the Wednesday night drawing, said Chuck Strutt, executive director of the Multi-State Lottery Association.

The jackpot had already rolled over 16 consecutive times without a winner, but Powerball officials said earlier Wednesday they believed there was a 75 percent chance the winning combination will be drawn this time.

If one ticket hits the right numbers, chances are good that multiple ones will, according to some experts. That happened in the Mega Millions drawing in March, when three ticket buyers shared a $656 million jackpot, which remains the largest lottery payout of all time.

Yvette Gavin, who sold the tickets to Fallie, is only an occasional lottery player herself, but the huge jackpot means she'll definitely play this time. As for the promises she often gets from ticket purchasers, Gavin isn't holding her breath.

"A lot of customers say if they win they will take care of me, but I will have to wait and see," she said.

In the hours before Wednesday's drawing, Associated Press photographers across the nation sought out ticket buyers and asked about their lottery fantasies. Here's a look at what they found:

___

When Atlanta barber Andre Williams buys scratch-off tickets, he typically does a dance in his shop for good luck. As a first-time Powerball player, he plans to reprise the dance — and buy a few extra tickets to enhance his chances.

I don't even know if I'll look at it," said Williams, who bought his ticket at a newsstand. "If I win, I might pass out."

Paralegal Pat Powell was buying her first Powerball ticket at another store in Atlanta, even though she acknowledged her odds were probably "zero to zero."

Still, Powell has specific plans should she win: start an Internet cafe in the West Indies and a learning center in Georgia.

"I've been thinking about winning this money and what I'd do with it," Powell said. "There's no ritual, but it's just been on my mind. So it's like, let me just join the hype and just do it."

Atlanta accountant Benita Lewis, who had never played the lottery before, didn't want to be the only one left in her office without a ticket.

"I did feel nervous buying it like I could be the one," she said. "I'm going to retire and pay off all my family's debt."

___

In Philadelphia, seafood salesman Billy Fulginiti bought 50 Powerball tickets with co-workers and a few more with a small group. He said he only plays when the jackpot is especially large.

"You go to bed at night wishing you wake up a millionaire," Fulginiti said. He planned to take a long vacation and "help a lot of people, a lot of charities," if any of his tickets turn out to be winners.

___

Powerball purchases at the Canterbury Country Store in Canterbury, N.H., have been so steady that the manager has been working extra evening hours to keep up.

Horticulturist Kevin Brags buys tickets at the store two to three times a month. He says he usually picks numbers higher than 32 because so many people use numbers 31 and lower, largely because of birthdays.

The birthday theory didn't scare off Paul Kruzel, a retired doctor who chooses the days his children were born.

Both, however, have the same plans for winning: "make a lot of people happy."

John Olson has a more elaborate idea: He'd like to buy an island.

___

At a downtown Detroit convenience store, Ceejay Johnson purchased five Powerball tickets. If she strikes it rich, the analyst from Southfield, Mich., said she would buy a home for her sister in Florida. Then she would "go into hiding" and take care of her family.

"And the IRS," she added.

___

Associated Press photographer Jim Cole reported from Canterbury, N.H.

___

Associated Press photographers Paul Sancya in Detroit, David Goldman in Atlanta and Matt Rourke in Philadelphia, and AP writers David Pitt in Des Moines, Iowa, and Jeff McMurray in Chicago contributed to this report.


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Rugby-England add flyhalf Burns to squad for All Blacks’ test












LONDON, Nov 27 (Reuters) – England called up uncapped Gloucester flyhalf Freddie Burns on Tuesday to their squad for Saturday’s test against New Zealand in place of the injured Toby Flood.


Flood sustained ligament damage to a big toe during the 16-15 loss to South Africa at Twickenham last Saturday.












Owen Farrell, whose last start was in the first test in South Africa this year, is set to replace Flood in the starting XV against the world champions.


Lock Courtney Lawes, who missed England’s first three tests of the November series because of a knee injury, has also been included in the 23-man squad. Two other locks, Mouritz Botha and Tom Palmer, have been omitted.


After beating Fiji in their opening match, England have lost to Australia and the Springboks and now face a daunting match against the All Blacks who are unbeaten in 20 tests since the start of their victorious World Cup campaign last year.


“For those in Saturday’s squad the message is clear – last week we went toe to toe with the second best team in the world and felt we should have won,” England head coach Stuart Lancaster said in a statement.


“Now we have a chance to take on the number one side in front of a passionate Twickenham crowd, who have been fantastic throughout the Internationals, and it is a challenge we will meet head on.” (Reporting by John Mehaffey; Editing by Ken Ferris)


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Ex-Elmo puppeteer faces new sex-with-minor allegation












NEW YORK (Reuters) – The puppeteer formerly behind the “Sesame Street” character Elmo faces a new accusation of having sex with an underage boy, a week after a similar allegation prompted him to resign from the iconic public television children’s program.


In a lawsuit filed Tuesday in U.S. District Court in Manhattan, a man identified only as John alleges Kevin Clash engaged in oral sex and other sex acts with him when John was 16 years old. The suit seeks at least $ 75,000 in damages.












The suit alleges the incident occurred in either 2000 or 2001 when John, who is from Florida, visited New York for modeling opportunities. John came to know Clash, then 40, through a telephone chat line for gays on which Clash claimed to be a 30-year-old named Craig, according to the suit.


John returned to New York when he turned 18, and he and Clash renewed the relationship, the lawsuit said.


“Mr. Clash believes the lawsuit has no merit,” Clash’s publicist, Risa B. Heller, said in an emailed statement.


It is the latest charge levied against Clash, now 52, who resigned on November 20 from Sesame Workshop, the company behind “Sesame Street,” after nearly 30 years on the show.


His resignation came the same day Cecil Singleton filed a claim seeking more than $ 5 million in damages from Clash. Singleton claims he met the then-32-year-old puppeteer in 1993 in a gay chat room when he was 15.


It added that on numerous occasions over a period of years Clash engaged in sexual activity with Singleton.


The newest allegation comes about two weeks after another man recanted his claims that Clash had sex with him when he was 16 years old. The man later said the relationship was consensual.


Clash had denied the allegations and acknowledged a past relationship with his first accuser. He added the pair were both consenting adults at the time.


The Elmo character debuted on “Sesame Street” in 1979, 10 years after the show premiered and introduced the now-iconic characters Big Bird, Bert and Ernie, Oscar the Grouch and Cookie Monster, among others, to American children.


While Clash was the third performer to animate the child-like shaggy red monster, Sesame Workshop credits him with turning Elmo into the international sensation he became.


(Reporting by Dan Burns; Editing by Paul Thomasch and Cynthia Osterman)


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Flu Symptoms Drove Boston Mayor to Hospital












When Boston Mayor Thomas Menino ended his vacation in Italy short this fall and checked into a Boston hospital complaining of a respiratory infection, it led doctors to find and treat a blood clot in his leg, a fracture in his back, an infection around the fracture and type 2 diabetes.


Cold and flu symptoms from respiratory infections can be a hassle, but sometimes that fever and cough can be good for just getting people to the doctor.












“That’s why every patient needs a careful evaluation because every once in a while, what the patient thinks is the flu or reports as the flu is not,” said Dr. William Schaffner, chairman of preventative medicine at Vanderbilt University in Tennessee. “I would say 99 percent of people who present to the emergency room and doctor’s office with symptoms of influenza – that is cough, fever and the like – are certainly going to have influenza.”


Click here to read about cold- and flu-fighters.


Menino, 69, arrived at Brigham and Women’s Hospital on Oct. 25, complaining of fatigue and a cough, and doctors described him as “extremely washed out” with some “malaise.” In addition to the respiratory infection, doctors found a blood clot that traveled from Menino’s leg to his lungs.


Respiratory illnesses, like the one that initially drove Menino to seek medical attention, can often range from mild to severe, Schaffner said.


“He was feeling poorly enough to end what was supposed to be a very pleasant vacation, and when he got here, he was very weak and very washed out,” Dr. Dale Adler, Menino’s doctor, said during a press conference in mid-November.


Doctors can usually tell whether flu-like symptoms are the result of a respiratory infection or something else soon after the patient is admitted. If not, they can perform a series of tests to find out.


Click here to read about flu fact and fiction.


(The flu can lead to other ailments, the most common of which is pneumonia, or an infection of the lungs, Schaffner said.


About 1.1 million pneumonia patients were hospitalized and discharged in 2009, according to the latest data from the Centers for Disease Control and Prevention. On average, they stayed in the hospital 5.2 days.)


Weeks later, Menino was still in the hospital. Although his illness and clot had been resolved, he was complaining of back pain, which doctors discovered was the result of a compression fracture and an infection around the fracture.


Finally, doctors discovered that Menino had underlying type 2 diabetes, which may have contributed to the infection, Menino’s doctor said during a press conference on Monday.


It’s not clear how Menino’s initial flu-like symptoms tied into his other ailments, but doctors said they are positive about his prognosis. The mayor relocated to a rehabilitation center on Monday.


“It is a run of bad luck,” Morris said of Menino. “He will rebound from this.”


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Protesters pack Tahrir Square, dispute Morsi

CAIRO (AP) — The same chants used against Hosni Mubarak were turned against his successor Tuesday as more than 200,000 people packed Egypt's Tahrir Square in the biggest challenge yet to Islamist President Mohammed Morsi.


The massive, flag-waving throng protesting Morsi's assertion of near-absolute powers rivaled some of the largest crowds that helped drive Mubarak from office last year.


"The people want to bring down the regime!" and "erhal, erhal" — Arabic for "leave, leave" — rang out across the plaza, this time directed at Egypt's first freely elected president.


The protests were sparked by edicts Morsi issued last week that effectively neutralize the judiciary, the last branch of government he does not control. But they turned into a broader outpouring of anger against Morsi and his Muslim Brotherhood, which opponents say have used election victories to monopolize power, squeeze out rivals and dictate a new, Islamist constitution, while doing little to solve Egypt's mounting economic and security woes.


Clashes broke out in several cities, with Morsi's opponents attacking Brotherhood offices, setting fire to at least one. Protesters and Brotherhood members pelted each other with stones and firebombs in the Nile Delta city of Mahalla el-Kobra, leaving at least 100 people injured.


"Power has exposed the Brotherhood. We discovered their true face," said Laila Salah, a housewife at the Tahrir protest who said she voted for Morsi in last summer's presidential election. After Mubarak, she said, Egyptians would no longer accept being ruled by an autocrat.


"It's like a wife whose husband was beating her and then she divorces him and becomes free," she said. "If she remarries she'll never accept another day of abuse."


Gehad el-Haddad, a senior adviser to the Brotherhood and its political party, said Morsi would not back down on his edicts. "We are not rescinding the declaration," he told The Associated Press.


That sets the stage for a drawn-out battle that could throw the nation into greater turmoil. Protest organizers have called for another mass rally Friday. If the Brotherhood responds with demonstrations of its own, as some of its leaders have hinted, it would raise the prospect of greater violence after a series of clashes between the two camps in recent days.


A tweet by the Brotherhood warned that if the opposition was able to bring out 200,000 to 300,000, "they should brace for millions in support" of Morsi.


Another flashpoint could come Sunday, when the constitutional court is to rule on whether to dissolve the assembly writing the new constitution, which is dominated by the Brotherhood and its Islamist allies. Morsi's edicts ban the courts from disbanding the panel; if the court defies him and rules anyway, it would be a direct challenge that could spill over into the streets.


"Then we are in the face of the challenge between the supreme court and the presidency," said Nasser Amin, head of the Arab Center for the Independence of the Judiciary and the Legal Profession. "We are about to enter a serious conflict" on both the legal and street level, he said.


Morsi and his supporters say the decrees were necessary to prevent the judiciary from blocking the "revolution's goals" of a transition to democracy. The courts — where many Mubarak-era judges still hold powerful posts — have already disbanded the first post-Mubarak elected parliament, which was led by the Brotherhood. Now it could also take aim at the Islamist-led upper house of parliament.


Morsi's decrees ban the judiciary from doing so and grant his decisions immunity from judicial review. Morsi also gave himself sweeping powers to prevent threats to the revolution, stability or state institutions, which critics say are tantamount to emergency laws. These powers are to remain in effect until the constitution is approved and parliamentary elections are held, not likely before spring 2013.


Opponents say the decrees turn Morsi — who narrowly won last summer's election with just over 50 percent of the vote — into a new dictator, given that he holds not only executive but also legislative powers, after the lower house of parliament was dissolved.


Tuesday's turnout was an unprecedented show of strength by the mainly liberal and secular opposition, which has been divided and uncertain amid the rise to power of the Brotherhood over the past year. The crowds were of all stripes, including many first-time protesters.


"Suddenly Morsi is issuing laws and becoming the absolute ruler, holding all powers in his hands," said Mona Sadek, a 31-year-old engineering graduate who wears the Islamic veil, a hallmark of piety. "Our revolt against the decrees became a protest against the Brotherhood as well."


"The Brotherhood hijacked the revolution," agreed Raafat Magdi, an engineer who was among a crowd of some 10,000 marching from the Cairo district of Shubra to Tahrir to the beat of drums and chants against the Brotherhood. Reform leader Mohammed ElBaradei led the march.


"People woke up to (Morsi's) mistakes, and in any new elections they will get no votes," Magdi said.


Many in the crowd said they were determined to push ahead with the protests until Morsi retreats. A major concern was that Islamists would use the decree's protection of the constitutional assembly to drive through their vision for the next charter, with a heavy emphasis on implementing Shariah, or Islamic law. The assembly has been plagued with controversy, and more than two dozen of its 100 members have quit in recent days to protest Islamist control.


"Next Friday will be decisive," protester Islam Bayoumi said of the upcoming rally. "If people maintain the same pressure and come in large numbers, they could manage to press the president and rescue the constitution."


A fellow protester, Saad Salem Nada, said of Morsi: "I am a Muslim and he made me hate Muslims because of the dictatorship in the name of religion. In the past, we had one Mubarak. Now we have hundreds."


Even as the crowds swelled in Tahrir, clashes erupted nearby between several hundred protesters throwing stones and police firing tear gas on a street leading to the U.S. Embassy. Clouds of tear gas hung over the area, where clashes have broken out for several days, fueled by anger over police abuses.


A photographer working for the AP, Ahmed Gomaa, was beaten by stick-wielding police while covering the clashes. Police took his equipment and Gomaa was taken to a hospital for treatment.


Rival rallies by Morsi opponents and supporters turned into brief clashes in the Mediterranean city of Alexandria, where anti-Morsi protesters broke into the local office of the Muslim Brotherhood, throwing furniture out the windows and trying unsuccessfully to set fire to it. Protesters also set fire to Brotherhood offices in the city of Mansoura.


Morsi's supporters canceled a massive rally planned for Tuesday in Cairo, citing the need to "defuse tension." Morsi's supporters say more than a dozen of their offices have been ransacked or set ablaze since Friday. Some 5,000 demonstrated in the southern city of Assiut in support of Morsi's decrees, according to witnesses there.


So far, there has been little sign of a compromise. On Monday, Morsi met with the nation's top judges and tried to win their acceptance of his decrees. But the move was dismissed by many in the opposition and the judiciary as providing no real concessions.


Saad Emara, a senior Muslim Brotherhood member, said Morsi will not make any concessions, especially after the surge of violence and assaults on Brotherhood offices.


Emara accused the opposition "of resorting to violence with a political cover," claiming that former ruling party and Mubarak-era businessmen were hiring thugs to attack Brotherhood offices with the opposition's blessing.


"The story now is that the civilian forces are playing with fire. This is a dangerous scene."


___


Associated Press writer Hamza Hendawi in Cairo contributed to this report.

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Dog days in Cuba: from shih tzus to schnauzers












HAVANA (AP) — The Cuban capital has played host to political summits and art festivals, ballet tributes and international baseball competitions. Now dog lovers are getting their chance to take center stage.


Hundreds of people from all over Cuba and several other countries came to a scruffy field near Revolution Plaza this past week to preen and fuss over the shih tzus, beagles, schnauzers and cocker spaniels that are the annual Fall Canine Expo’s star attractions. There were even about a dozen bichon habaneros, a mid-sized dog bred on the island since the 17th century.












As dog lovers talked shop, the merely curious strolled the field, checking out the more than 50 breeds on display while carefully dodging the prodigious output of so many dogs.


The four-day competition, which ended Sunday, included competitions in several breeding categories, and judges were flown in from Nicaragua, Colombia and Mexico.


“This is a small, poor country, but Cubans love dogs,” said Miguel Calvo, the president of Cuba’s dog federation, which organized the show. “We make a great effort to breed purebred animals of quality.”


Winners don’t receive any trophy or prize money, but that doesn’t mean the competition is any less fierce.


Anabel Perez, owner of a cocker spaniel named Lisamineli after the U.S. actress, spent more than half an hour coifing the dog’s hair in preparation for the competition, while the owner of a shih tzu named Tiguer meticulously brushed his coat nearby.


“I’m a hairdresser for humans,” explained Tiguer’s owner, Miguel Lopez. “So it’s easy for me. I like shih tzus because they are a lot of work to keep well groomed.”


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Beyonce to direct documentary about herself for HBO












LOS ANGELES (Reuters) – Pop superstar Beyonce is stepping behind the camera to direct a behind-the-scenes documentary about her personal and professional life, U.S. cable channel HBO said on Monday.


The currently untitled film will debut on February 16 and show the Grammy-winning singer’s life in the recording studio, readying for live performances and running her own TV and music production company.












“Everybody knows Beyonce’s music, but few know Beyonce the person,” HBO Programming President Michael Lombardo said in a statement. “Along with electrifying footage of Beyonce on stage, this unique special looks beyond the glamour to reveal a vibrant, vulnerable, unforgettable woman.”


The documentary will also feature moments in the “Crazy in Love” singer’s family life and first-person footage Beyonce captured on her laptop.


Beyonce, 31, who is married to hip hop artist and mogul Jay-Z, will headline the Super Bowl halftime show in New Orleans on February 3.


(Reporting By Eric Kelsey, editing by Jill Serjeant and Andrew Hay)


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HIV Vaccine Under Study May Last A Lifetime












A genetically-engineered HIV vaccine under study by Texas researchers works in a novel way.


It targets specific cells exactly where the virus enters the body, stimulating them to generate an immune response so the virus can’t take hold.












If the strategy bears out, the vaccine will be a single dose and last a lifetime, says Marie-Claire Gauduin, PhD, assistant scientist at Texas Biomedical Research Institute.


”Many other HIV vaccines try to block the infection when the virus is already in,” she says.  ”Here we try not to be infected to begin with,” Gauduin tells Take Part.


RELATED: Breakthrough: Early HIV Treatment Virtually Erases Risk of Passing Virus On


About 33 million people worldwide are living with  HIV/AIDS, according to estimates by the Joint United Nations Programme on HIV/AIDS.  Most do not know it. The new vaccine, if perfected, could be given to children at puberty to stem this toll, Gauduin says.


Most new cases of HIV infections worldwide are transmitted by sexual intercourse through outer layers of cells known as epithelial cells. These line the surfaces of structures throughout the body.


The target of the new vaccine is the mucosal layers of the epithelium in the genital and rectal areas, where the virus  typically enters.


“We are targeting the basal layer, the lower layer of epithelial stem cells,” she says. These stem cells divide and differentiate into specialized cell types.


The vaccine stays put in the epithelial stem cells, she says. Next, antigens that recognize the virus are produced.  ”These antigens stimulate your immune response to fight the virus,” she says.


“The virus will be recognized at the site of entry,” she says. “The virus won’t get to the blood stream is the hope.”


What makes it long lasting, she says, is the initial targeting of the stem cells. “Once the epithelial stem cell gets the message to stimulate your immune response, it will do so constantly,” she says, so the virus will be recognized long term.


Gauduin and her colleagues recently filed for a patent on the approach.


The vaccine, of course, is years from clinical practice, she says. “We have a lot of work to do,” she tells Take Part. Primate studies may start in early 2013. Human trials may begin as early as 2015.


Currently, other HIV vaccine approaches can’t deliver the antibody production for long periods of time. So the protection is weak and temporary, Gauduin says.


“It looks very interesting, certainly a great idea,” say Yegor Voronin, PhD, science officer for Global HIV Vaccine Enterprise, an alliance devoted to developing a preventive HIV vaccine.


RELATED: FDA Approves Truvada as First HIV Prevention Drug


The approach makes sense to scientists like him. “Epithelial cells don’t live very long,” he says. “They are continuously shed off. They are trying to affect the stem cells that produce epithelial cells. As the stem cells differentiate into epithelial cells, that is when they start producing the antigen.”


“It’s very early stages,” he says. “It’s an excellent idea. Whether it will work–who knows?”


Many other attempts have not panned out, he says.


One important as-yet unanswered question, he says, is whether the vaccine could cause some sort of health problem ”and you have the antigen being expressed continuously.” He asks: “How are you going to turn that off?”


Much safety testing, among other research, will be needed, he says.


As with other vaccines under development, he says a wait-and-see stance is best. “At this point, it’s just way too early to tell.”



Kathleen Doheny is a Los Angeles journalist who writes about health. She doesn’t believe inmiracle cures, but continues to hope someone will discover a way for joggers to maintain their pace.


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